Top Endocrine Publications of 2013: The Feline Adrenal Gland

In my next compilation of the canine and feline endocrine publications of 2013, I’m moving on to disorders of the feline adrenal gland.

Listed below are 12 research papers written in 2013 that deal with a variety of adrenal gland topics of issues of clinical importance in cats.

These range from a study of body condition on the bioavailability of prednisone and prednisolone in cats (1) to investigation of adrenal gland ultrasonography in normal and sick cats (2); from a study that designed an oral fludrocortisone suppression test for diagnosis of hyperaldosteronism (Conn's syndrome) in cats (3) to another that designed a corticotropin-releasing hormone (CRH) protocol for evaluation of the hypothalamic-pituitary-adrenal axis (4); and from a study which measured cortisol levels in cats' hair (5) to a case report of ACTH-secreting pituitary carcinoma causing Cushing's disease in a cat (6).

Other studies included a retrospective study of trilostane treatment of cats with Cushing's disease (7) to a review of hyperadrenocorticism and diabetes mellitus in cats (8); from studies of the effects of stress on glucocorticoid metabolites (9) to a case report of a cat with double GH- and ACTH-secreting pituitary adenomas (10); and finally, from a case report of a cat that presented in Addisonian crisis (11) to an investigation of the renin-angiotensin-aldosterone system in hyperthyroid cats with and without hypertension (12).

References:

1. Center SA, Randolph JF, Warner KL, et al. Influence of body condition on plasma prednisolone and prednisone concentrations in clinically healthy cats after single oral dose administration. Res Vet Sci 2013;95:225-230. 
2. Combes A, Pey P, Paepe D, et al. Ultrasonographic appearance of adrenal glands in healthy and sick cats. J Feline Med Surg 2013;15:445-457. 
3. Djajadiningrat-Laanen SC, Galac S, Boeve SAEB, et al. Evaluation of the oral fludrocortisone suppression test for diagnosing primary hyperaldosteronism in cats. J Vet Intern Med 2013;27:1493-1499. 
4. Eiler KC, Bruyette DS, Behrend EN, et al. Comparison of intravenous versus intramuscular administration of corticotropin-releasing hormone in healthy cats. J Vet Intern Med 2013;27:516-521. 
5. Galuppi R, Leveque JF, Beghelli V, et al. Cortisol levels in cats' hair in presence or absence of Microsporum canis infection. Res Vet Sci 2013;95:1076-1080. 
6. Kimitsuki K, Boonsriroj H, Kojima D, et al. A case report of feline pituitary carcinoma with hypercortisolism. J Vet Med Sci 2014;76:133-138. 
7. Mellett Keith AM, Bruyette D, Stanley S. Trilostane therapy for treatment of spontaneous hyperadrenocorticism in cats: 15 cases (2004-2012). J Vet Intern Med 2013;27:1471-1477. 
8. Niessen SJ, Church DB, Forcada Y. Hypersomatotropism, acromegaly, and hyperadrenocorticism and feline diabetes mellitus. Vet Clin North Am Small Anim Pract 2013;43:319-350. 
9. Ramos D, Reche-Junior A, Fragoso PL, et al. Are cats (Felis catus) from multi-cat households more stressed? Evidence from assessment of fecal glucocorticoid metabolite analysis. Physiol Behav 2013;122:72-75. 
10. Sharman M, FitzGerald L, Kiupel M. Concurrent somatotroph and plurihormonal pituitary adenomas in a cat. J Feline Med Surg 2013;15:945-952. 
11. Sicken J, Neiger R. Addisonian crisis and severe acidosis in a cat: a case of feline hypoadrenocorticism. J Feline Med Surg 2013;15:941-944. 
12. Williams TL, Elliott J, Syme HM. Renin-angiotensin-aldosterone system activity in hyperthyroid cats with and without concurrent hypertension. J Vet Intern Med 2013;27:522-529.