Top Endocrine Publications of 2011: Canine and Feline Endocrine Nutrition

In my 10th and last compilation of the canine and feline endocrine publications of 2011, I’m finishing up with endocrine nutrition and treatment of obesity in dogs and cats. Starting in February of the New Year, I'm planning to start posting the endocrine publications for 2012. I'm only waiting for the final papers published in December to come out so they can be included in my lists and reviews.

Listed below are 27 research papers written in 2011 that deal with a variety of topics of clinical importance concerning endocrine nutrition or obesity in the dog and cat. Remember that adipose tissue is the largest endocrine gland in the body, making a number of hormones, including leptin, adiponectin, and resistin. These hormones generally influence energy metabolism, which is of great interest to the understanding and treatment of type 2 diabetes and obesity.

These papers range from the studies of the effects of neutering on body weight and body composition in cats (1,2) to studies of the glucose intolerance and insulin resistance associated with obesity (3, 20-22); from the cause, prevalence, and management of obesity in dogs and cats (5,8-10,25,26) to the effect of nutrition and dietary water on calcium oxalate and stuvite in cats (4,7).

Other research studies include the influence of dietary composition on the circulating glucose and insulin response to feeding (6,11-13) to factors that regulate serum leptin and adiponectin concentrations in dogs and cats (16-18,22-24). Finally, this lists also includes two excellent review papers on feline nutrition (15,27) — where we are reminded that cats are true carnivores and need higher amounts of protein, and not carbs!

References:

1. Alexander LG, Salt C, Thomas G, et al. Effects of neuteringon food intake, body weight and body composition in growing female kittens. Br J Nutr 2011;106 Suppl 1:S19-23. 
2. Backus R. Plasma oestrogen changes in adult male cats afterorchiectomy, body-weight gain and low-dosage oestradiol administration. Br J Nutr 2011;106 Suppl 1:S15-18. 
3. Brunetto MA, Sa FC, Nogueira SP, et al. The intravenous glucose tolerance and postprandial glucose tests may present different responses in the evaluation of obese dogs. Br J Nutr 2011;106 Suppl 1:S194-197. 
4. Buckley CM, Hawthorne A, Colyer A, et al. Effect of dietary water intake on urinary output, specific gravity and relative supersaturation for calcium oxalate and struvite in the cat. Br J Nutr 2011;106 Suppl 1:S128-130. 
5. Chauvet A, Laclair J, Elliott DA, et al. Incorporation of exercise, using an underwater treadmill, and active client education into a weight management program for obese dogs. Can Vet J 2011;52:491-496. 
6. Coradini M, Rand JS, Morton JM, et al. Effects of twocommercially available feline diets on glucose and insulin concentrations,insulin sensitivity and energetic efficiency of weight gain. Br J Nutr 2011;106 Suppl 1:S64-77. 
7. Dijcker JC, Plantinga EA, van Baal J, et al. Influence ofnutrition on feline calcium oxalate urolithiasis with emphasis on endogenousoxalate synthesis. Nutr Res Rev 2011:1-15. 
8. German AJ. Canine obesity--weighing on the mind of the owner? J Small Anim Pract 2011;52:619-620. 
9. German AJ, Holden SL, Gernon LJ, et al. Do feeding practices of obese dogs, before weight loss, affect the success of weight management? Br J Nutr 2011;106 Suppl 1:S97-100. 
10. German AJ, Holden SL, Mather NJ, et al. Low-maintenance energy requirements of obese dogs after weight loss. Br J Nutr 2011;106 Suppl 1:S93-96. 
11. Hewson-Hughes AK, Gilham MS, Upton S, et al. Postprandialglucose and insulin profiles following a glucose-loaded meal in cats and dogs. Br J Nutr 2011;106 Suppl 1:S101-104. 
12. Hewson-Hughes AK, Gilham MS, Upton S, et al. The effect ofdietary starch level on postprandial glucose and insulin concentrations in catsand dogs. Br J Nutr 2011;106 Suppl 1:S105-109.
13. Hoenig M, Jordan ET, Glushka J, et al. Effect of macronutrients, age, and obesity on 6- and 24-h postprandial glucose metabolism in cats. Am J Physiol Regul Integr Comp Physiol 2011;301:R1798-1807. 
14. Ryan VH, Trayhurn P, Hunter L, et al. 11-Hydroxy-beta-steroid dehydrogenase gene expression in canine adipose tissue and adipocytes: stimulation by lipopolysaccharide and tumor necrosis factor alpha. Domest Anim Endocrinol 2011;41:150-161. 
15. Sparkes AH. Feeding old cats—an update on new nutritional therapies. Top Companion Anim Med 2011;26:37-42. 
16. Tan HY, Rand JS, Morton JM, et al. Adiponectin profiles areaffected by chronic and acute changes in carbohydrate intake in healthy cats. General & Comparative Endocrinology 2011;172:468-474. 
17.  Tvarijonaviciute A, Ceron JJ, Martinez-Subiela S. Assessment of five ELISAs for measurement of leptin concentrations in dogs. Am J Vet Res 2011;72:169-173. 
18. Tvarijonaviciute A, Eralp O, Kocaturk M, et al. Adiponectin and IGF-1 are negative acute phase proteins in a dog model of acute endotoxaemia. Vet Immunol Immunopathol 2011;140:147-151. 
19. Tvarijonaviciute A, Tecles F, Carillo JM, et al. Serum insulin-like growth factor-1 measurements in dogs: performance characteristics of an automated assay and study of some sources of variation. Can J Vet Res 2011;75:312-316. 
20. Verkest KR, Fleeman LM, Morton JM, et al. Compensation for obesity-induced insulin resistance in dogs: assessment of the effects of leptin, adiponectin, and glucagon-like peptide-1 using path analysis. Domest Anim Endocrinol 2011;41:24-34. 
21. Verkest KR, Fleeman LM, Rand JS, et al. Evaluation of beta-cell sensitivity to glucose and first-phase insulin secretion in obese dogs. Am J Vet Res 2011;72:357-366. 
22. Verkest KR, Rand JS, Fleeman LM, et al. Distinct adiponectin profiles might contribute to differences in susceptibility to type 2 diabetes in dogs and humans. Domest Anim Endocrinol 2011;41:67-73. 
23. Verkest KR, Rose FJ, Fleeman LM, et al. Adiposity and adiponectin in dogs: investigation of causes of discrepant results between two studies. Domest Anim Endocrinol 2011;41:35-41. 
24. Wakshlag JJ, Struble AM, Levine CB, et al. The effects of weight loss on adipokines and markers of inflammation in dogs. Br J Nutr 2011;106 Suppl 1:S11-14. 
25. Warren BS, Wakshlag JJ, Maley M, et al. Use of pedometers to measure the relationship of dog walking to body condition score in obese and non-obese dogs. Br J Nutr 2011;106 Suppl 1:S85-89. 
26. White GA, Hobson-West P, Cobb K, et al. Canine obesity: is there a difference between veterinarian and owner perception? J Small Anim Pract 2011;52:622-626. 
27. Zoran DL, Buffington CA. Effects of nutrition choices and lifestyle changes on the well-being of cats, a carnivore that has moved indoors. J Am Vet Med Assoc 2011;239:596-606.