Thursday, August 4, 2011

Top Endocrine Publications of 2010: The Canine and Feline Reproductive Endocrinology

 Fertility axis. GnRH, LH & FSH
stimulate secretion of testosterone,
progesterone, estrogen, & inhibin.
Controlled via negative feedback
on hypothalamus & pituitary gland.
In my 9th compilation of the canine and feline endocrine publications of 2010, I’m moving on to endocrine disorders of the canine gonads and mammary gland.

Listed below are 9 research papers written in 2010 that deal with a variety of issues of clinical importance in reproductive endocrinology in dogs.

These range from the investigations of the pituitary-ovarian axis in dogs with a functional granulosa cell tumor (1) to studies of the expression of estrogen and progesterone receptors in sebaceous gland tumors (2); and from studies of gonadotropin-releasing hormone (GnRH)-agonist implants in the treatment of reproductive disorders in the male dog (3) to a review of non-surgical methods for reproductive control in cats (4).

Finally, a number of studies investigate markers of malignancy for mammary gland tumors (6,7,8). Finally, the last paper reviews alternative ways to treat benign prostatic hyperplasia, including hormonal suppression of testicular function with GnRH-depot-analogues, inhibition of the 5-alpha-reductase, or peripheral androgen action with anti-androgens (9).

  1. Buijtels JJ, de Gier J, Kooistra HS, et al. Alterations of the pituitary-ovarian axis in dogs with a functional granulosa cell tumor. Theriogenology 2010;73:11-19.
  2. Ginel PJ, Lucena R, Millan Y, et al. Expression of oestrogen and progesterone receptors in canine sebaceous gland tumours. Veterinary Dermatology 2010;21:297-302.
  3. Goericke-Pesch S, Wilhelm E, Ludwig C, et al. Evaluation of the clinical efficacy of Gonazon implants in the treatment of reproductive pathologies, behavioral problems, and suppression of reproductive function in the male dog. Theriogenology 2010;73:920-926.
  4. Goericke-Pesch S. Reproduction control in cats: new developments in non-surgical methods. J Feline Med Surg. 2010 12:539-46
  5. Groppetti D, Pecile A, Arrighi S, et al. Endometrial cytology and computerized morphometric analysis of epithelial nuclei: a useful tool for reproductive diagnosis in the bitch. Theriogenology 2010;73:927-941.
  6. Klopfleisch R, Klose P, Gruber AD. The combined expression pattern of BMP2, LTBP4, and DERL1 discriminates malignant from benign canine mammary tumors. Veterinary Pathology 2010;47:446-454.
  7. Millanta F, Caneschi V, Ressel L, et al. Expression of vascular endothelial growth factor in canine inflammatory and non-inflammatory mammary carcinoma. Journal of Comparative Pathology 2010;142:36-42.
  8. Queiroga FL, Perez-Alenza D, Silvan G, et al. Serum and intratumoural GH and IGF-I concentrations: prognostic factors in the outcome of canine mammary cancer. Research in Veterinary Science 2010;89:396-403.
  9. Renggli M, Padrutt I, Michel E, et al. Benign prostatic hyperplasia: treatment options in the dog. Schweizer Archiv fur Tierheilkunde 2010;152:279-284.

No comments: