tag:blogger.com,1999:blog-1020386515354656609.post5182859982480056067..comments2024-03-19T15:11:11.769-04:00Comments on Insights into Veterinary Endocrinology: Q & A: Pituitary Macrotumor in a Dog with Cushing's DiseaseDr. Mark E. Petersonhttp://www.blogger.com/profile/10804290441832222507noreply@blogger.comBlogger4125tag:blogger.com,1999:blog-1020386515354656609.post-23931271387692012012014-12-24T20:46:02.283-05:002014-12-24T20:46:02.283-05:00Unfortunately, I don't have any answers here. ...Unfortunately, I don't have any answers here. The PU/PD could be due to undertreated Di, but that could also be associated with the glucocorticoid treatment. My main concern is the poor appetite... if the tumor has been destroyed, then CNS infiltration of tumor should have not be the cause. You need to talk to your internist and radiation oncologist about these issues.Dr. Mark E. Petersonhttps://www.blogger.com/profile/10804290441832222507noreply@blogger.comtag:blogger.com,1999:blog-1020386515354656609.post-37185340027989250132014-12-23T21:45:00.093-05:002014-12-23T21:45:00.093-05:00Hi Dr Peterson,
My 5 year old male Whippet just co...Hi Dr Peterson,<br />My 5 year old male Whippet just completed 20 IMRT 10 weeks ago for a pituitary tumor. He was also diagnosed with DI, and Hypothyroidism (borderline to true). Since weaning him off Prednisone he has somewhat remained having PU/PD, and has pretty profound inappetence. He is taking Desmopressin BID and Soloxine BID. We also just added an appetite stimulant & Prilosec (in case of nausea). Could the inappetence be due to the Hypothalamus or hunger part of the brain being affected by the tumor or the radiation? He had body shivers or tremors also during the weeks of IMRT and while still on the Pred, but those have subsided and he is otherwise active, and has no other illness symptoms. Should we increase Desmopressin dose? He is 42lbs. and receives 0.1mg BID. Any thoughts or advice is greatly appreciated. He is a great dog. Thank you in advance. Karynhttps://www.blogger.com/profile/02317205258529201142noreply@blogger.comtag:blogger.com,1999:blog-1020386515354656609.post-16175902506462439102013-06-04T08:36:50.681-04:002013-06-04T08:36:50.681-04:00Without seeing your dog and reveiwing the images, ...Without seeing your dog and reveiwing the images, I can't really answer your questions. Most dogs respond at least partially to radiation therapy. But that takes a few weeks to months to have any effect so we use medication (either trilostane or mitotane) to control signs (increased thirst and urination, etc), if needed.<br /><br />Overall, if neurologic signs are present, the prognosis with pituitary macrotumors is guarded to poor. I'd talk to your veterinarian and see a neurologist and radiation oncologist for more information about how to treat your dog and the long-term prognosis.Dr. Mark E. Petersonhttps://www.blogger.com/profile/10804290441832222507noreply@blogger.comtag:blogger.com,1999:blog-1020386515354656609.post-84541171315226989272013-06-04T00:09:22.820-04:002013-06-04T00:09:22.820-04:00My Boston Terrier, age 8 has just been diagnosed w...My Boston Terrier, age 8 has just been diagnosed with a 13 mm macroadenoma. She is not taking any medications for Cushings. She was dx last week after neck surgery. Her neck was still hurting so the surgeon did a CT. My questions are general. Do dogs take Cushings medication with Radiation? Is radiation ever successful with large tumors? My dog is showing very mild neuro changes. I just thought she was aging. Distant staring, takes awhile to climb stairs, not very active. How do most dogs pass? Related to side effects of medications & liver issues or the brain tumor becoming too large? I just want a general idea of what to look out for if we don't begin medication. Just your past experience. Thank you, Pixie's Mom, WendyAnonymoushttps://www.blogger.com/profile/04439373120437152226noreply@blogger.com