tag:blogger.com,1999:blog-1020386515354656609.post4966989677255513679..comments2024-03-19T15:11:11.769-04:00Comments on Insights into Veterinary Endocrinology: Q & A: Pacing and Circling in a Cushing's Dog Treated with TrilostaneDr. Mark E. Petersonhttp://www.blogger.com/profile/10804290441832222507noreply@blogger.comBlogger7125tag:blogger.com,1999:blog-1020386515354656609.post-27089169498042467552015-09-01T08:40:54.415-04:002015-09-01T08:40:54.415-04:00I do not know of any studies that looked at combin...I do not know of any studies that looked at combined use of selegiline with trilostane. I would not anticipate an Addison's crisis since selegiline is not very effective for pituitary-dependent Cushing's disease, but I do not know for certain.Dr. Mark E. Petersonhttps://www.blogger.com/profile/10804290441832222507noreply@blogger.comtag:blogger.com,1999:blog-1020386515354656609.post-23325472475595569832015-08-31T18:10:40.266-04:002015-08-31T18:10:40.266-04:00Have you found any studies supporting the use of s...Have you found any studies supporting the use of selegiline (for cognitive dysfunction syndrome) with trilostane (for Cushing's)? Would you be worried about Addisonian crisis (even though selegiline does not affect adrenal glands) or do you have experience with the combination?Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-1020386515354656609.post-47685871844459625792015-08-08T14:52:27.615-04:002015-08-08T14:52:27.615-04:00Sounds like more than cognitive dysfunction to me....Sounds like more than cognitive dysfunction to me. I'd recommend a consult with a veterinary neurologist if you haven't already done so. Talk to your vet.Dr. Mark E. Petersonhttps://www.blogger.com/profile/10804290441832222507noreply@blogger.comtag:blogger.com,1999:blog-1020386515354656609.post-35647890747950443932015-08-08T08:06:38.687-04:002015-08-08T08:06:38.687-04:00my dog is 16 years and I just start to use selegil...my dog is 16 years and I just start to use selegiline for canine cognitive dysfunction. The problem is the continuous circling. There's a way to avoid it? What can I do? May Seleginine stop circling? Or there are other therapies? <br /><br />thanksMorgan21752https://www.blogger.com/profile/11957342735847710630noreply@blogger.comtag:blogger.com,1999:blog-1020386515354656609.post-54857433803899569432014-11-18T00:41:32.661-05:002014-11-18T00:41:32.661-05:00Jo: what happened? Is your dog back on vetoryl?Jo: what happened? Is your dog back on vetoryl?Anonymoushttps://www.blogger.com/profile/11921292096841840109noreply@blogger.comtag:blogger.com,1999:blog-1020386515354656609.post-10410373348863939702014-05-14T20:37:22.136-04:002014-05-14T20:37:22.136-04:00Canine pituitary tumors grow up (dorsally) into th...Canine pituitary tumors grow up (dorsally) into the main portion of the brain. Unlike human patients, dog pituitary tumors do not grow ventrally and invade bone. So no, a head x-ray would not help diagnose a pituitary tumor in a dog.<br /><br />Dogs with Cushing's disease can rarely develop facial nerve palsy (the 7th cranial nerve). This is not associated with or caused by a pituitary tumor. Your vet can easily diagnosis that condition on examination.<br /><br />We do not understand the cause of the 7th nerve palsy in Cushing's and there is no treatment, other than supportive care.Dr. Mark E. Petersonhttps://www.blogger.com/profile/10804290441832222507noreply@blogger.comtag:blogger.com,1999:blog-1020386515354656609.post-33188094913168620332014-05-14T15:54:49.448-04:002014-05-14T15:54:49.448-04:00Couldn't an X-Ray show a large mass for a pitu...Couldn't an X-Ray show a large mass for a pituitary tumor as well to show it as being a macro sized tumor? <br /><br />My dog was recently diagnosed with Cushing's, after starting Vetoryl 60mg, he started drooling and seemed to have a nerve problem with the left side of his tongue...also, he went into an Addison's crisis from an overdose. Right now he's OK..but off the Vetoryl for now, and taking Predisone now 10mg until symptoms start again..and will be given another ACTH Stim test before he's started back on the Vetoryl, but at a much lower dose this time. I'm still concerned about his mouth, although, he's stopped drooling for now...his tongue problem is still there. Could that be a side effect of the Cushing's?? Anonymoushttps://www.blogger.com/profile/13894568408392123452noreply@blogger.com