Top Endocrine Publications of 2013: Hypertension in Dogs and Cats

In my sixth compilation of the canine and feline endocrine publications of 2013, I’m moving on to endocrine hypertension. Listed below are 13 research papers written in 2013 that deal with a variety of hypertensive topics of clinical importance, many of which directly involve one or more hormones.

These range from a review of the hypertension associated with diabetic nephropathy (1) to an overview of guidelines for antihypertensive therapy in dogs and cats (2); from diagnostic testing of primary hyperaldosteronism in cats (3) to the use of plasma metanephrines for diagnosis of pheochromocytoma in dogs (5); and from a case study of a dog that develop severe hypertension secondary to an overdose of phenylpropanolamine (4) to a study of the relationship between the degree of hypertension and the development of ocular changes in cats with chronic kidney disease (6).

Other publications included are a comparison of indirect blood pressure measurements using a non-invasive method, high-definition oscillometry to direct measurements using a radio-telemetry device in awake cats (7) to a study of the effect of body position on indirect measurement of systolic arterial blood pressure in dogs (10);  from a report of a case series of dogs and cats with hypertensive encephalopathy (8) to a study of the effect of intra-abdominal hypertension on the adrenal gland secretion of cortisol, aldosterone, epinephrine, and norepinephrine in dogs (13); and finally, from a report of high dietary salt intake and blood pressure in cats (9) to an investigation of the renin-angiotensin-aldosterone system in the pathogenesis of hypertension associated with hyperthyroidism in cats (12).

References:

1. Bloom CA, Rand JS. Diabetes and the kidney in human and veterinary medicine. Vet Clin North Am Small Anim Pract 2013;43:351-365. 
2. Buoncompagni S, Bowles MH. Treatment of systemic hypertension associated with kidney disease. Compend Contin Educ Vet 2013;35:E1. 
3. Djajadiningrat-Laanen SC, Galac S, Boeve SAEB, et al. Evaluation of the oral fludrocortisone suppression test for diagnosing primary hyperaldosteronism in cats. J Vet Intern Med 2013;27:1493-1499. 
4. Ginn JA, Bentley E, Stepien RL. Systemic hypertension and hypertensive retinopathy following PPA overdose in a dog. J Am Anim Hosp Assoc 2013;49:46-53. 
5. Green BA, Frank EL. Comparison of plasma free metanephrines between healthy dogs and 3 dogs with pheochromocytoma. Vet Clin Pathol 2013;42:499-503. 
6. Karck J, von Spiessen L, Rohn K, et al. Interrelation between the degree of a chronic renal insufficiency and/or systemic hypertension and ocular changes in cats. Tierarztliche Praxis Ausgabe K, Kleintiere/Heimtiere 2013;41:37-45. 
7. Martel E, Egner B, Brown SA, et al. Comparison of high-definition oscillometry -- a non-invasive technology for arterial blood pressure measurement -- with a direct invasive method using radio-telemetry in awake healthy cats. J Feline Med Surg 2013; 15:1104-1115. 
8. O'Neill J, Kent M, Glass EN, et al. Clinicopathologic and MRI characteristics of presumptive hypertensive encephalopathy in two cats and two dogs. J Am Anim Hosp Assoc 2013;49:412-420. 
9. Reynolds BS, Chetboul V, Nguyen P, et al. Effects of dietary salt intake on renal function: a 2-year study in healthy aged cats. J Vet Intern Med 2013;27:507-515. 
10. Rondeau DA, Mackalonis ME, Hess RS. Effect of body position on indirect measurement of systolic arterial blood pressure in dogs. J Am Vet Med Assoc 2013;242:1523-1527. 
11. Tian Z, Shen Y, Liao H, et al. Carotid proliferative plaque formation in a canine model of chronic hypertension. J Investig Med 2013;61:995-1003. 
12. Williams TL, Elliott J, Syme HM. Renin-angiotensin-aldosterone system activity in hyperthyroid cats with and without concurrent hypertension. J Vet Intern Med 2013;27:522-529. 
13. Yu J, Fu X, Chang M, et al. The effects of intra-abdominal hypertension on the secretory function of canine adrenal glands. PLoS One 2013;8:e81795.